Oncological results of salvage laryngectomy in patients with laryngeal carcinoma

Xavier León, Victoria Montoro, Carlota Rovira, Eduard Neumann, Montserrat López, Jacinto García, Miquel Quer

Research output: Contribution to journalArticleResearch

3 Citations (Scopus)

Abstract

© 2019 Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello Objective: To analyse the oncological results of a salvage total laryngectomy in patients with a laryngeal carcinoma. Material and methods: Retrospective review of a cohort of 241 patients treated with a salvage laryngectomy after a local recurrence. The initial treatment received by these patients was radiotherapy (n = 201, 83.4%), chemoradiotherapy (n = 19, 7.9%), and partial surgery (n = 21, 8.7%), Results: Total laryngectomy as salvage treatment achieved local control of the disease in 81.3% of cases, with a 5-year specific survival of 65.3%. The variables related with specific survival in a univariate analysis were the location of the primary tumour, the local extension of the initial tumour and of the recurrence, the resection margins, and the pathological status of the neck dissections. According to the results of a multivariate analysis, the variables related to specific survival were the status of the resection margins, the presence of simultaneous regional recurrence, and the local extension of the recurrence. Conclusion: The 5-year specific survival of patients treated with a salvage laryngectomy was 65.3%. The variables related with the control of the disease were the status of the resection margins, the presence of simultaneous regional recurrence and the local extension of the recurrence.
Original languageEnglish
JournalActa Otorrinolaringologica Espanola
DOIs
Publication statusPublished - 1 Jan 2019

Keywords

  • Laryngeal carcinoma
  • Local recurrence
  • Radiotherapy
  • Salvage surgery
  • Total laryngectomy

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