On the role of the cytoskeleton in coccolith morphogenesis: The effect of cytoskeleton inhibitors

Gerald Langer, Lennart Jan De Nooijer, Kerstin Oetjen

    Research output: Contribution to journalArticleResearchpeer-review

    26 Citations (Scopus)

    Abstract

    The coccolithophore Emiliania huxleyi (Lohmann) W. W. Hay et H. Mohler was cultured in natural seawater with the addition of either the microtubule-inhibitor colchicine, the actin-inhibitor cytochalasin B, or the photosynthesis inhibitor 3-(3,4 dichlorophenyl)-1,1-dimethyl-urea (DCMU). Additionally, E. huxleyi was cultured at different light intensities and temperatures. Growth rate was monitored, and coccolith morphology analyzed. While every treatment affected growth rate, the percentage of malformed coccoliths increased with colchicine, cytochalasin B, and at higher than optimal temperature. These results represent the first experimental evidence for the role of microtubules and actin microfilaments in coccolith morphogenesis. © 2010 Phycological Society of America.
    Original languageEnglish
    Pages (from-to)1252-1256
    JournalJournal of Phycology
    Volume46
    Issue number6
    DOIs
    Publication statusPublished - 1 Jan 2010

    Keywords

    • Biomineralization
    • Coccolith morphogenesis
    • Coccolithophores
    • Colchicine
    • Cytochalasin B
    • Cytoskeleton

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