On the primary structure of membrane-bound semicarbazide-sensitive amine oxidase (SSAO)

J. M. Lizcano, M. Unzeta

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

Mammalian semicarbazide-sensitive amine oxidase (SSAO) activities are a diverse group of copper dependent enzymes within the classification EC 1.4.3.6. [amine:oxygen oxidoreductase (deaminating) (copper-containing)]. They include plasma amine oxidase and the membrane-bound enzyme. Although soluble plasma SSAO from several species have been successfully purified and cloned, relatively little work has been carried out on the molecular properties of the tissue-bound enzyme. At present there is not conclusive evidence that allows to conclude whether or not plasma SSAO is released from the tissue-bound enzyme. This review focuses upon recent progress made in determining the primary structure of the membrane-bound SSAO.
Original languageEnglish
Pages (from-to)37-46
JournalNeurobiology
Volume8
Issue number1
Publication statusPublished - 26 Sep 2000

Keywords

  • Amine metabolism
  • Copper
  • Glycoprotein
  • Semicarbazide-sensitive amine oxidase
  • Topa quinone

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