Oesophageal motility disorders in infected immigrants with Chagas disease in a non-endemic European area

Sílvia Roure, Lluís Valerio, Xavier Vallès, Betty Morales, M. Immaculada Garcia-Diaz, M. Luisa Pedro-Botet, Jordi Serra

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5 Citations (Scopus)


© 2016, © Author(s) 2016. Background: Immigration-related new diseases pose a growing challenge for healthcare services in receptor countries. Following Latin American migration, Chagas disease has inevitably appeared in Europe. Aim: To determine the prevalence and characteristics of oesophageal motility disorders in immigrants infected with Trypanosoma cruzi, using high resolution oesophageal manometry (HREM). Methods: In all newly-diagnosed cases with chronic Chagas infection referring upper digestive symptoms, a protocolized clinical evaluation and complementary tests including barium oesophagogram and HREM were carried out. As control group, 14 healthy subjects from the same endemic areas were studied with HREM. Results: We included 61 patients (46 female, 15 male; age range 26–63 years). Only seven patients (11%) had a minor alteration on barium oesophagogram. By contrast, 23 (37%) patients showed an alteration in oesophageal manometry, mainly minor motility disorders (34%). Only one healthy control (7%) had a minor motility disorder at HREM (p = 0.029 vs. patients). Conclusions: Oesophageal motor disorders in infected immigrants with Chagas disease are common, and mainly characterized by a minor motility disorder that is not detected by barium oesophagogram. Hence, as well as barium oesophagogram examination, HREM should be considered, to assess oesophageal damage in this specific group of patients.
Original languageEnglish
Pages (from-to)614-620
JournalUnited European Gastroenterology Journal
Issue number4
Publication statusPublished - 1 Aug 2016


  • American trypanosomiasis
  • Chagas disease
  • dysphagia
  • high resolution manometry
  • oesophageal motility disorders
  • Trypanosoma cruzi


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