Occupational asthma due to colistin in a pharmaceutical worker

Susana Gómez-Ollés; Federico Madrid-San Martín; María Jesús Cruz; Xavier Muñoz

doi:10.1378/chest.09-1881

Occupational asthma due to colistin in a pharmaceutical worker

Susana Gómez-Ollés, Federico Madrid-San Martín, María Jesús Cruz, Xavier Muñoz

Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)

Abstract

To our knowledge, this is the first case report of a 24-year-old man working in a pharmaceutical company transporting and storing raw materials who developed occupational asthma (OA) to colistin. The specific inhalation challenge confirmed the diagnosis of OA to colistin. Specific IgE was not detected, because dot-blot analysis was negative at all colistin concentrations tested. To our knowledge, OA due to a peptide antibiotic has not previously been described. This antibiotic should be listed as a trigger of OA. © 2010 American College of Chest Physicians.

Original language	English
Pages (from-to)	1200-1202
Journal	Chest
Volume	137
Issue number	5
DOIs	https://doi.org/10.1378/chest.09-1881
Publication status	Published - 1 May 2010

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abstract = "To our knowledge, this is the first case report of a 24-year-old man working in a pharmaceutical company transporting and storing raw materials who developed occupational asthma (OA) to colistin. The specific inhalation challenge confirmed the diagnosis of OA to colistin. Specific IgE was not detected, because dot-blot analysis was negative at all colistin concentrations tested. To our knowledge, OA due to a peptide antibiotic has not previously been described. This antibiotic should be listed as a trigger of OA. {\textcopyright} 2010 American College of Chest Physicians.",

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N2 - To our knowledge, this is the first case report of a 24-year-old man working in a pharmaceutical company transporting and storing raw materials who developed occupational asthma (OA) to colistin. The specific inhalation challenge confirmed the diagnosis of OA to colistin. Specific IgE was not detected, because dot-blot analysis was negative at all colistin concentrations tested. To our knowledge, OA due to a peptide antibiotic has not previously been described. This antibiotic should be listed as a trigger of OA. © 2010 American College of Chest Physicians.

AB - To our knowledge, this is the first case report of a 24-year-old man working in a pharmaceutical company transporting and storing raw materials who developed occupational asthma (OA) to colistin. The specific inhalation challenge confirmed the diagnosis of OA to colistin. Specific IgE was not detected, because dot-blot analysis was negative at all colistin concentrations tested. To our knowledge, OA due to a peptide antibiotic has not previously been described. This antibiotic should be listed as a trigger of OA. © 2010 American College of Chest Physicians.

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