Neuroblastoma (NB) is the most common solid tumour in children and adolescents, and accounts for up to 15% of all cancer deaths in this group. It originates in the sympathetic nervous system, and its behaviour can be very aggressive and become resistant to current treatments. A review is presented, summarising the new alternative therapies based on epigenetics, i.e., modulators of gene expression, such as microRNAs and their potential application in the clinical practice of NB treatment.
|Translated title of the contribution||Novel micro RNA-based therapies for the treatment of neuroblastoma|
|Journal||Anales de Pediatria|
|Publication status||Published - 1 Aug 2016|