Novel Dent disease 1 cellular models reveal biological processes underlying ClC-5 loss-of-function

Keyphrases

• Biological Processes 100%
• Loss Function 100%
• Cellular Models 100%
• Dent Disease 1 100%
• ClC-5 100%
• Pathophysiology 28%
• Proximal Tubule Dysfunction 28%
• Organic Acids 14%
• Gene Expression Profile 14%
• Antiporter 14%
• Functional Traits 14%
• Chronic Kidney Disease 14%
• Extracellular Matrix Organization 14%
• Cell Migration 14%
• Gene Set Enrichment Analysis 14%
• Genotype-phenotype Correlation 14%
• Epithelial Phenotype 14%
• Hypercalciuria 14%
• Renal Tubular Epithelial Cells 14%
• Substrate Adhesion 14%
• Nephrocalcinosis 14%
• Proximal Tubule 14%
• Tubular Atrophy 14%
• X-linked 14%
• Ion Homeostasis 14%
• Acid Transport 14%
• Nephrolithiasis 14%
• Matrix Cell 14%
• Collective Migration 14%
• Low Molecular Weight Proteinuria 14%
• Kidney Development 14%
• RPTEC 14%
• Albumin Endocytosis 14%
• Endocytic Uptake 14%
• Proximal Tubulopathy 14%

Medicine and Dentistry

• Biological Phenomena and Functions Concerning the Entire Organism 100%
• Cellular Model 100%
• Dent's Disease 100%
• Pathophysiology 28%
• Extracellular Matrix 14%
• Gene Expression 14%
• Chronic Kidney Disease 14%
• Homeostasis 14%
• Proteinuria 14%
• Albumin 14%
• Genotype Phenotype Correlation 14%
• Kidney Tubule Disorder 14%
• Kidney Stone 14%
• Endocytosis 14%
• Hypercalciuria 14%
• Nephrocalcinosis 14%
• Tubular Dysfunction 14%
• Antiporter 14%
• Kidney Development 14%
• Cell Line 14%
• Cell Migration 14%
• Carboxylic Acid 14%
• Diseases 14%
• Genome-Wide Analysis of Gene Expression 14%