Noninvasive diagnosis of liver fibrosis in patients with HIV infection and HCV/HBV co-infection

S. Moreno; J. García-Samaniego; A. Moreno; E. Ortega; J. A. Pineda; J. Del Romero; C. Tural; M. A. Von Wichmann; J. Berenguer; Á Castro; R. Espacio

doi:10.1111/j.1365-2893.2009.01088.x

Noninvasive diagnosis of liver fibrosis in patients with HIV infection and HCV/HBV co-infection

S. Moreno, J. García-Samaniego, A. Moreno, E. Ortega, J. A. Pineda, J. Del Romero, C. Tural, M. A. Von Wichmann, J. Berenguer, Á Castro, R. Espacio

Department of Medicine

Research output: Contribution to journal › Review article › Research › peer-review

28 Citations (Scopus)

Abstract

Summary. The measurement of fibrosis stage critically affects the identification of the progression of liver disease, the establishment of a prognosis and therapeutic decision making. Liver biopsy has been the single, most useful method to determine the degree of liver fibrosis (LF), but with recognized limitations, mainly associated with its invasiveness. In recent years, alternative noninvasive methods have been developed, including imaging methods, such as transient elastometry, and assays based on serum biomarkers. This article reviews the available studies evaluating the value of various noninvasive methods for the assessment of LF in patients with HIV-infection and HBV/HCV co-infection, and makes recommendations on how to best use and combine them in clinical practice. © 2009 Blackwell Publishing Ltd.

Original language	English
Pages (from-to)	249-258
Journal	Journal of Viral Hepatitis
Volume	16
Issue number	4
DOIs	https://doi.org/10.1111/j.1365-2893.2009.01088.x
Publication status	Published - 1 Apr 2009

Keywords

Elastometry
HIV/HCV co-infection
Liver biopsy
Liver fibrosis
Serum markers

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1365-2893.2009.01088.x

Cite this

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title = "Noninvasive diagnosis of liver fibrosis in patients with HIV infection and HCV/HBV co-infection",

abstract = "Summary. The measurement of fibrosis stage critically affects the identification of the progression of liver disease, the establishment of a prognosis and therapeutic decision making. Liver biopsy has been the single, most useful method to determine the degree of liver fibrosis (LF), but with recognized limitations, mainly associated with its invasiveness. In recent years, alternative noninvasive methods have been developed, including imaging methods, such as transient elastometry, and assays based on serum biomarkers. This article reviews the available studies evaluating the value of various noninvasive methods for the assessment of LF in patients with HIV-infection and HBV/HCV co-infection, and makes recommendations on how to best use and combine them in clinical practice. {\textcopyright} 2009 Blackwell Publishing Ltd.",

keywords = "Elastometry, HIV/HCV co-infection, Liver biopsy, Liver fibrosis, Serum markers",

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doi = "10.1111/j.1365-2893.2009.01088.x",

language = "English",

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pages = "249--258",

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TY - JOUR

T1 - Noninvasive diagnosis of liver fibrosis in patients with HIV infection and HCV/HBV co-infection

AU - Moreno, S.

AU - García-Samaniego, J.

AU - Moreno, A.

AU - Ortega, E.

AU - Pineda, J. A.

AU - Del Romero, J.

AU - Tural, C.

AU - Von Wichmann, M. A.

AU - Berenguer, J.

AU - Castro, Á

AU - Espacio, R.

PY - 2009/4/1

Y1 - 2009/4/1

N2 - Summary. The measurement of fibrosis stage critically affects the identification of the progression of liver disease, the establishment of a prognosis and therapeutic decision making. Liver biopsy has been the single, most useful method to determine the degree of liver fibrosis (LF), but with recognized limitations, mainly associated with its invasiveness. In recent years, alternative noninvasive methods have been developed, including imaging methods, such as transient elastometry, and assays based on serum biomarkers. This article reviews the available studies evaluating the value of various noninvasive methods for the assessment of LF in patients with HIV-infection and HBV/HCV co-infection, and makes recommendations on how to best use and combine them in clinical practice. © 2009 Blackwell Publishing Ltd.

AB - Summary. The measurement of fibrosis stage critically affects the identification of the progression of liver disease, the establishment of a prognosis and therapeutic decision making. Liver biopsy has been the single, most useful method to determine the degree of liver fibrosis (LF), but with recognized limitations, mainly associated with its invasiveness. In recent years, alternative noninvasive methods have been developed, including imaging methods, such as transient elastometry, and assays based on serum biomarkers. This article reviews the available studies evaluating the value of various noninvasive methods for the assessment of LF in patients with HIV-infection and HBV/HCV co-infection, and makes recommendations on how to best use and combine them in clinical practice. © 2009 Blackwell Publishing Ltd.

KW - Elastometry

KW - HIV/HCV co-infection

KW - Liver biopsy

KW - Liver fibrosis

KW - Serum markers

U2 - 10.1111/j.1365-2893.2009.01088.x

DO - 10.1111/j.1365-2893.2009.01088.x

M3 - Review article

SN - 1352-0504

VL - 16

SP - 249

EP - 258

JO - Journal of Viral Hepatitis

JF - Journal of Viral Hepatitis

IS - 4

ER -

Noninvasive diagnosis of liver fibrosis in patients with HIV infection and HCV/HBV co-infection

Abstract

Keywords

UN SDGs

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