Abstract
Relative syn 1,2-hydrazinoalcohols have been prepared through diastereoselective Ni(II)-catalyzed Michael addition of chiral derivatives of acetoacetic acid and of 3-oxostearic acid to dialkyl azodicarboxylates, followed by stereoselective reduction of the keto function. © 2002 Elsevier Science Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 5699-5708 |
Journal | Tetrahedron |
Volume | 58 |
Issue number | 28 |
DOIs | |
Publication status | Published - 8 Jul 2002 |
Keywords
- Chiral induction
- Conjugate addition
- Kinetic resolution
- Nickel catalysis
- Syn-1,2-hydrazinoalcohol
- β-ketoacid derivatives