New triazole antifungal agents derived from mercaptomethylisoxazoles

M. Moreno-Mañas, Y. Arredondo, R. Pleixats, M. Teixidó, M. M. Raga, C. Palacín, J. M. Castelló, J. A. Ortiz

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Abstract

Several new triazole antifungal agents derived from mercaptomethylisoxazoles of general structure 2-(2,4-dihalogenophenyl)3-((X-isoxazolyl)methylthio)1-(1,2,4-triazol-1-yl)-2-propanol, as well as some selected sulfoxides and sulfones derived thereof, have been synthesized and tested for antifungal activity. Some of these compounds showed good activity against yeasts and dermatophytes.
Original languageEnglish
Pages (from-to)1557-1560
JournalJournal of Heterocyclic Chemistry
Volume29
Issue number6
DOIs
Publication statusPublished - 1 Oct 1992

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