New materials for electrochemical sensing V: Nanoparticles for DNA labeling

A. Merkoçi; M. Aldavert; S. Marín; S. Alegret

doi:10.1016/j.trac.2004.11.007

New materials for electrochemical sensing V: Nanoparticles for DNA labeling

A. Merkoçi, M. Aldavert, S. Marín, S. Alegret

Department of Chemistry

Research output: Contribution to journal › Article › Research › peer-review

139 Citations (Scopus)

Abstract

We present recent trends and challenges in the use of nanoparticles as DNA labels in electrochemical detection systems. We discuss nanoparticle synthesis procedures and methods for attaching biological molecules that enable their application in genosensors. We also discuss typical electrochemical procedures based on gold nanoparticles and quantum dots (QDs), along with QD carriers, such as carbon nanotube or polystyrene beads. High sensitivity and selectivity, simultaneous detection of various DNA sequences, and cost-efficient detection are advantages that seem to come using these novel labels in DNA electrochemical detection schemes. © 2004 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	341-349
Journal	TrAC - Trends in Analytical Chemistry
Volume	24
Issue number	4
DOIs	https://doi.org/10.1016/j.trac.2004.11.007
Publication status	Published - 1 Jan 2005

Keywords

DNA
Electrochemical sensing
Genosensors
Nanoparticles
QD
Quantum dots
Semiconductors
Stripping potentiometry
Stripping voltammetry

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title = "New materials for electrochemical sensing V: Nanoparticles for DNA labeling",

abstract = "We present recent trends and challenges in the use of nanoparticles as DNA labels in electrochemical detection systems. We discuss nanoparticle synthesis procedures and methods for attaching biological molecules that enable their application in genosensors. We also discuss typical electrochemical procedures based on gold nanoparticles and quantum dots (QDs), along with QD carriers, such as carbon nanotube or polystyrene beads. High sensitivity and selectivity, simultaneous detection of various DNA sequences, and cost-efficient detection are advantages that seem to come using these novel labels in DNA electrochemical detection schemes. {\textcopyright} 2004 Elsevier Ltd. All rights reserved.",

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AU - Merkoçi, A.

AU - Aldavert, M.

AU - Marín, S.

AU - Alegret, S.

PY - 2005/1/1

Y1 - 2005/1/1

N2 - We present recent trends and challenges in the use of nanoparticles as DNA labels in electrochemical detection systems. We discuss nanoparticle synthesis procedures and methods for attaching biological molecules that enable their application in genosensors. We also discuss typical electrochemical procedures based on gold nanoparticles and quantum dots (QDs), along with QD carriers, such as carbon nanotube or polystyrene beads. High sensitivity and selectivity, simultaneous detection of various DNA sequences, and cost-efficient detection are advantages that seem to come using these novel labels in DNA electrochemical detection schemes. © 2004 Elsevier Ltd. All rights reserved.

AB - We present recent trends and challenges in the use of nanoparticles as DNA labels in electrochemical detection systems. We discuss nanoparticle synthesis procedures and methods for attaching biological molecules that enable their application in genosensors. We also discuss typical electrochemical procedures based on gold nanoparticles and quantum dots (QDs), along with QD carriers, such as carbon nanotube or polystyrene beads. High sensitivity and selectivity, simultaneous detection of various DNA sequences, and cost-efficient detection are advantages that seem to come using these novel labels in DNA electrochemical detection schemes. © 2004 Elsevier Ltd. All rights reserved.

KW - DNA

KW - Electrochemical sensing

KW - Genosensors

KW - Nanoparticles

KW - QD

KW - Quantum dots

KW - Semiconductors

KW - Stripping potentiometry

KW - Stripping voltammetry

U2 - 10.1016/j.trac.2004.11.007

DO - 10.1016/j.trac.2004.11.007

M3 - Article

VL - 24

SP - 341

EP - 349

IS - 4

ER -