New imidazole anti-fungal agents derived from benzo[b]thiophene. Part II

Marcial Moreno-Mañas, Ma Rosa Cuberes, Celia Palacín, Manuel Raga, Josep M. Castello, JoséA Ortiz

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Abstract

1-[(Aryl)(benzo[b]thienyl)methyl]-1H-imidazoles 22, 1-[(benzo[b]thien-3-yl)(thienyl)methyl]-1H-imidazoles 25 and 1-[(diaryl)(benzo[b]thien-3-yl)methyl]-1H-imidazoles 28 have been synthesized and tested for anti-fungal activity. All compounds showed good activity against a broad spectrum of fungi (yeasts, dermatophytes). © 1988.
Original languageEnglish
Pages (from-to)477-482
JournalEuropean Journal of Medicinal Chemistry
Volume23
Issue number5
DOIs
Publication statusPublished - 1 Jan 1988

Keywords

  • anti-fungal activity
  • benzo[b]thienyl anti-fungal agents
  • imidazole anti-fungal agents
  • structure-activity relationships

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