TY - JOUR
T1 - New chromosomal abnormality. t(1;19;?) in a case of B-chronic lymphocytic leukemia
AU - Montero, Sergi
AU - Caballín, M. Rosa
AU - Coll, M. Dolors
AU - Besses, Carles
AU - Woessner, Soledad
AU - Egozcue, Josep
AU - Solé, Francesc
PY - 1992/1/1
Y1 - 1992/1/1
N2 - Cytogenetic analysis was performed on peripheral blood cells stimulated with interleukin 6 (IL-6), lipopolysaccharide from Escherichia coli (LPS), phytohemagglutinin (PHA), pokeweed mitogen (PWM) and tetradecanoyl-phorbol-acetate (TPA), in a patient with B-chronic lymphocytic leukemia, showing a t(1;19;?) translocation as the sole abnormality. To our knowledge, this translocation has not been described before in any human neoplasia. In this case, the poor response to therapy (survival time 4 months) suggested that t(1;19;?) could be related to an aggressive course of the disease. © 1992.
AB - Cytogenetic analysis was performed on peripheral blood cells stimulated with interleukin 6 (IL-6), lipopolysaccharide from Escherichia coli (LPS), phytohemagglutinin (PHA), pokeweed mitogen (PWM) and tetradecanoyl-phorbol-acetate (TPA), in a patient with B-chronic lymphocytic leukemia, showing a t(1;19;?) translocation as the sole abnormality. To our knowledge, this translocation has not been described before in any human neoplasia. In this case, the poor response to therapy (survival time 4 months) suggested that t(1;19;?) could be related to an aggressive course of the disease. © 1992.
U2 - 10.1016/0165-4608(92)90004-R
DO - 10.1016/0165-4608(92)90004-R
M3 - Article
SN - 0165-4608
VL - 60
SP - 131
EP - 134
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
IS - 2
ER -
