New chiral polyfunctional cyclobutane derivatives from (-)-verbenone: Possible surfactant behaviour

Jimena Ospina, Alessandro Sorrenti, Ona Illa, Ramon Pons, Rosa M. Ortuño

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)


New enantiopure cyclobutane derivatives have been synthesized from a chiral precursor derived from (-)-verbenone. The cyclobutane moiety acts as a chiral platform to afford a γ-amino acid function in a branched side-chain containing an additional stereogenic centre as well as additional C6 or C16-alkyl chains linked to the ring by means of an amine or an amide function. One of these compounds, obtained as a 1:2 mixture with its TFA salt has been investigated, suggesting behaviour as a good surfactant and its critical micellar concentration has been determined. © 2013 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)713-718
JournalTetrahedron Asymmetry
Issue number12
Publication statusPublished - 30 Jun 2013


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