NEU Screen Shows High Accuracy in Detecting Cognitive Impairment in Older Persons Living With HIV

Anna Prats; Estela López-Masramon; Núria Pérez-Álvarez; Maite Garolera; Carmina R. Fumaz; Maria J. Ferrer; Bonaventura Clotet; Jose A. Muñoz-Moreno

doi:10.1097/JNC.0000000000000003

NEU Screen Shows High Accuracy in Detecting Cognitive Impairment in Older Persons Living With HIV

Anna Prats, Estela López-Masramon, Núria Pérez-Álvarez, Maite Garolera, Carmina R. Fumaz, Maria J. Ferrer, Bonaventura Clotet, Jose A. Muñoz-Moreno

Department of Medicine

Research output: Contribution to journal › Article › Research

2 Citations (Scopus)

Abstract

The NEUrocognitive (NEU) Screen is a practical tool proposed to screen for HIV-associated cognitive impairment in the clinical setting. This is a pencil-and-paper method that can be applied rapidly (≤10 minutes for administration) and has no copyright limitations. In this study, we aimed at investigating its diagnostic accuracy in an older population of persons living with HIV (PLWH), with cutoffs set at 30, 40, 50, and 60 years. Data were collected from a sample of 368 PLWH who underwent a comprehensive neuropsychological tests battery (gold standard). Results of statistical tests showed that accuracy of the NEU Screen increased with age of the participants. The highest degree of precision, with a sensitivity of 91% and specificity of 92%, was obtained for people ages 60 years or older (correct classification: 91%). These optimal results point to the great potential of the NEU Screen as a tool for detecting cognitive disorders in older PLWH.

Original language	English
Pages (from-to)	35-41
Journal	The Journal of the Association of Nurses in AIDS Care : JANAC
Volume	30
DOIs	https://doi.org/10.1097/JNC.0000000000000003
Publication status	Published - 1 Jan 2019

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title = "NEU Screen Shows High Accuracy in Detecting Cognitive Impairment in Older Persons Living With HIV",

abstract = "The NEUrocognitive (NEU) Screen is a practical tool proposed to screen for HIV-associated cognitive impairment in the clinical setting. This is a pencil-and-paper method that can be applied rapidly (≤10 minutes for administration) and has no copyright limitations. In this study, we aimed at investigating its diagnostic accuracy in an older population of persons living with HIV (PLWH), with cutoffs set at 30, 40, 50, and 60 years. Data were collected from a sample of 368 PLWH who underwent a comprehensive neuropsychological tests battery (gold standard). Results of statistical tests showed that accuracy of the NEU Screen increased with age of the participants. The highest degree of precision, with a sensitivity of 91% and specificity of 92%, was obtained for people ages 60 years or older (correct classification: 91%). These optimal results point to the great potential of the NEU Screen as a tool for detecting cognitive disorders in older PLWH.",

author = "Anna Prats and Estela L{\'o}pez-Masramon and N{\'u}ria P{\'e}rez-{\'A}lvarez and Maite Garolera and Fumaz, {Carmina R.} and Ferrer, {Maria J.} and Bonaventura Clotet and Mu{\~n}oz-Moreno, {Jose A.}",

year = "2019",

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day = "1",

doi = "10.1097/JNC.0000000000000003",

language = "English",

volume = "30",

pages = "35--41",

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NEU Screen Shows High Accuracy in Detecting Cognitive Impairment in Older Persons Living With HIV. / Prats, Anna; López-Masramon, Estela; Pérez-Álvarez, Núria; Garolera, Maite; Fumaz, Carmina R.; Ferrer, Maria J.; Clotet, Bonaventura; Muñoz-Moreno, Jose A.

In: The Journal of the Association of Nurses in AIDS Care : JANAC, Vol. 30, 01.01.2019, p. 35-41.

Research output: Contribution to journal › Article › Research

TY - JOUR

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AU - Prats, Anna

AU - López-Masramon, Estela

AU - Pérez-Álvarez, Núria

AU - Garolera, Maite

AU - Fumaz, Carmina R.

AU - Ferrer, Maria J.

AU - Clotet, Bonaventura

AU - Muñoz-Moreno, Jose A.

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AB - The NEUrocognitive (NEU) Screen is a practical tool proposed to screen for HIV-associated cognitive impairment in the clinical setting. This is a pencil-and-paper method that can be applied rapidly (≤10 minutes for administration) and has no copyright limitations. In this study, we aimed at investigating its diagnostic accuracy in an older population of persons living with HIV (PLWH), with cutoffs set at 30, 40, 50, and 60 years. Data were collected from a sample of 368 PLWH who underwent a comprehensive neuropsychological tests battery (gold standard). Results of statistical tests showed that accuracy of the NEU Screen increased with age of the participants. The highest degree of precision, with a sensitivity of 91% and specificity of 92%, was obtained for people ages 60 years or older (correct classification: 91%). These optimal results point to the great potential of the NEU Screen as a tool for detecting cognitive disorders in older PLWH.

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