TY - JOUR
T1 - Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: A single-blind observational study
AU - Andreu, Montserrat
AU - Beltran, Javier Gimeno
AU - Álvarez-Gonzalez, Marco Antonio
AU - Urgorri, Agustín Seoane
AU - Dedeu, Josep Maria
AU - Priego, Luis Barranco
AU - Bessa, Xavier
AU - Pons, Fausto Riu
PY - 2018/12/7
Y1 - 2018/12/7
N2 - © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. AIM To assess the incremental benefit of narrow band imaging (NBI) and white light endoscopy (WLE), randomizing the initial technique for the detection of residual neoplasia at the polypectomy scar after an endoscopic piecemeal mucosal resection (EPMR). METHODS We conducted an observational study in an academic center to assess the incremental benefit of NBI and WLE randomly applied 1:1 (NBI-WLE or WLE-NBI) in the follow-up of a post-EPMR scar by the same endoscopist. RESULTS A total of 112 EPMR scars were included. The median baseline polyp size was 20 mm (interquartile range: 14-30). At first review, NBI and WLE showed good sensitivity (85.0% vs 78.9%), specificity (77.1% vs 84.2%) and overall accuracy (80.0% vs 82.5%). NBI after WLE (WLE-NBI group) improved accuracy, but this difference was not statistically significant [area under the curve (AUC): 86.8% vs 81.6%, P = 0.15]. WLE after NBI (NBI-WLE group) did not improve accuracy (AUC: 81.4% vs 81.1%, P = 0.9). Overall, recurrence was found in 39/112 (34.8%) lesions. CONCLUSION Although no statistically significant differences were found between the two techniques at the first post-EPMR assessment, the use of NBI after WLE may improve residual neoplasia detection. Nevertheless, biopsy is still required in the first scar review.
AB - © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. AIM To assess the incremental benefit of narrow band imaging (NBI) and white light endoscopy (WLE), randomizing the initial technique for the detection of residual neoplasia at the polypectomy scar after an endoscopic piecemeal mucosal resection (EPMR). METHODS We conducted an observational study in an academic center to assess the incremental benefit of NBI and WLE randomly applied 1:1 (NBI-WLE or WLE-NBI) in the follow-up of a post-EPMR scar by the same endoscopist. RESULTS A total of 112 EPMR scars were included. The median baseline polyp size was 20 mm (interquartile range: 14-30). At first review, NBI and WLE showed good sensitivity (85.0% vs 78.9%), specificity (77.1% vs 84.2%) and overall accuracy (80.0% vs 82.5%). NBI after WLE (WLE-NBI group) improved accuracy, but this difference was not statistically significant [area under the curve (AUC): 86.8% vs 81.6%, P = 0.15]. WLE after NBI (NBI-WLE group) did not improve accuracy (AUC: 81.4% vs 81.1%, P = 0.9). Overall, recurrence was found in 39/112 (34.8%) lesions. CONCLUSION Although no statistically significant differences were found between the two techniques at the first post-EPMR assessment, the use of NBI after WLE may improve residual neoplasia detection. Nevertheless, biopsy is still required in the first scar review.
KW - Colonoscopy
KW - Endoscopic mucosal resection
KW - Narrow band imaging
U2 - 10.3748/wjg.v24.i45.5179
DO - 10.3748/wjg.v24.i45.5179
M3 - Article
C2 - 30568394
VL - 24
SP - 5179
EP - 5188
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
SN - 1007-9327
ER -