TY - JOUR
T1 - Nanostructured Ti-Zr-Pd-Si-(Nb) bulk metallic composites: Novel biocompatible materials with superior mechanical strength and elastic recovery
AU - Hynowska, A.
AU - Blanquer, A.
AU - Pellicer, E.
AU - Fornell, J.
AU - Suriñach, S.
AU - Barõ, M. D.
AU - Gebert, A.
AU - Calin, M.
AU - Eckert, J.
AU - Nogués, C.
AU - Ibáñez, E.
AU - Barrios, L.
AU - Sort, J.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - © 2014 Wiley Periodicals, Inc. The microstructure, mechanical behaviour, and biocompatibility (cell culture, morphology, and cell adhesion) of nanostructured Ti45Zr15Pd35-xSi5Nbx with x = 0, 5 (at. %) alloys, synthesized by arc melting and subsequent Cu mould suction casting, in the form of rods with 3 mm in diameter, are investigated. Both Ti-Zr-Pd-Si-(Nb) materials show a multi-phase (composite-like) microstructure. The main phase is cubic β-Ti phase (Im3m) but hexagonal α-Ti (P63/mmc), cubic TiPd (Pm3m), cubic PdZr (Fm3m), and hexagonal (Ti, Zr)5Si3 (P63/mmc) phases are also present. Nanoindentation experiments show that the Ti45Zr15Pd30Si5Nb5 sample exhibits lower Young's modulus than Ti45Zr15Pd35Si5. Conversely, Ti45Zr15Pd35Si5 is mechanically harder. Actually, both alloys exhibit larger values of hardness when compared with commercial Ti-40Nb, (HTi-Zr-Pd-Si ≈ 14 GPa, HTi-Zr-Pd-Si-Nb ≈ 10 GPa and HTi-40Nb ≈ 2.7 GPa). Concerning the biological behaviour, preliminary results of cell viability performed on several Ti-Zr-Pd-Si-(Nb) discs indicate that the number of live cells is superior to 94% in both cases. The studied Ti-Zr-Pd-Si-(Nb) bulk metallic system is thus interesting for biomedical applications because of the outstanding mechanical properties (relatively low Young's modulus combined with large hardness), together with the excellent biocompatibility.
AB - © 2014 Wiley Periodicals, Inc. The microstructure, mechanical behaviour, and biocompatibility (cell culture, morphology, and cell adhesion) of nanostructured Ti45Zr15Pd35-xSi5Nbx with x = 0, 5 (at. %) alloys, synthesized by arc melting and subsequent Cu mould suction casting, in the form of rods with 3 mm in diameter, are investigated. Both Ti-Zr-Pd-Si-(Nb) materials show a multi-phase (composite-like) microstructure. The main phase is cubic β-Ti phase (Im3m) but hexagonal α-Ti (P63/mmc), cubic TiPd (Pm3m), cubic PdZr (Fm3m), and hexagonal (Ti, Zr)5Si3 (P63/mmc) phases are also present. Nanoindentation experiments show that the Ti45Zr15Pd30Si5Nb5 sample exhibits lower Young's modulus than Ti45Zr15Pd35Si5. Conversely, Ti45Zr15Pd35Si5 is mechanically harder. Actually, both alloys exhibit larger values of hardness when compared with commercial Ti-40Nb, (HTi-Zr-Pd-Si ≈ 14 GPa, HTi-Zr-Pd-Si-Nb ≈ 10 GPa and HTi-40Nb ≈ 2.7 GPa). Concerning the biological behaviour, preliminary results of cell viability performed on several Ti-Zr-Pd-Si-(Nb) discs indicate that the number of live cells is superior to 94% in both cases. The studied Ti-Zr-Pd-Si-(Nb) bulk metallic system is thus interesting for biomedical applications because of the outstanding mechanical properties (relatively low Young's modulus combined with large hardness), together with the excellent biocompatibility.
KW - Ti-based alloy
KW - bioimplant
KW - biological tests
KW - mechanical behaviour
KW - nanostructured material
U2 - https://doi.org/10.1002/jbm.b.33346
DO - https://doi.org/10.1002/jbm.b.33346
M3 - Article
SN - 1552-4973
VL - 103
SP - 1569
EP - 1579
JO - Journal of Biomedical Materials Research - Part B Applied Biomaterials
JF - Journal of Biomedical Materials Research - Part B Applied Biomaterials
ER -