Nanostructured CaCO3-poly(ethyleneimine) microparticles for phenol sensing in fluidic microsystem

Carmen C. Mayorga-Martinez, Lenka Hlavata, Sandrine Miserere, Adaris López-Marzo, Jan Labuda, Josefina Pons, Arben Merkoçi

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)


A new and simple strategy based on nanostructured CaCO3-poly(ethyleneimine) (PEI) microparticles (MPs) for phenol sensing using PDMS/glass fluidic microchip is developed. This fluidic microsystem including integrated screen-printed electrodes modified with CaCO3-PEI MPs and tyrosinase (Tyr) through cross-linking with glutaraldehyde, represents a low-cost platform for phenol detection. The designed fluidic microsystem improves the sensitivity of the biosensor allowing the detection of very low concentrations of phenol (up to 10 nM). This device shows high repeatability and low detection limit, is easy to be fabricated, inexpensive, disposable, and amenable to mass production. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Original languageEnglish
Pages (from-to)2011-2016
Issue number14
Publication statusPublished - 1 Jul 2013


  • Electrochemistry
  • Fluidic microsystem
  • Nanostructurated CaCO -poly(ethylene-imine) microparticles 3
  • Phenolic compounds


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