Nanoparticles for imaging, sensing, and therapeutic intervention

Lara K. Bogart; Genevieve Pourroy; Catherine J. Murphy; Víctor Puntes; Teresa Pellegrino; Daniel Rosenblum; Dan Peer; Rapäel Lévy

doi:10.1021/nn500962q

Nanoparticles for imaging, sensing, and therapeutic intervention

Lara K. Bogart, Genevieve Pourroy, Catherine J. Murphy, Víctor Puntes, Teresa Pellegrino, Daniel Rosenblum, Dan Peer, Rapäel Lévy

Research output: Contribution to journal › Article › Research › peer-review

276 Citations (Scopus)

Abstract

Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.

Original language	English
Pages (from-to)	3107-3122
Number of pages	16
Journal	ACS Nano
Volume	8
Issue number	4
DOIs	https://doi.org/10.1021/nn500962q
Publication status	Published - 2014

Keywords

Animal model
Biological media
Hybrid nanomaterials
Knowledge gaps
New modality
Physicochemical property
Surface design
Therapeutic intervention
Animals
Biocompatible Materials
Humans
Molecular Imaging
Nanomedicine
Nanoparticles

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/nn500962q

https://ddd.uab.cat/record/204820

Cite this

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abstract = "Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.",

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AU - Bogart, Lara K.

AU - Pourroy, Genevieve

AU - Murphy, Catherine J.

AU - Puntes, Víctor

AU - Pellegrino, Teresa

AU - Rosenblum, Daniel

AU - Peer, Dan

AU - Lévy, Rapäel

PY - 2014

Y1 - 2014

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AB - Nanoparticles have the potential to contribute to new modalities in molecular imaging and sensing as well as in therapeutic interventions. In this Nano Focus article, we identify some of the current challenges and knowledge gaps that need to be confronted to accelerate the developments of various applications. Using specific examples, we journey from the characterization of these complex hybrid nanomaterials; continue with surface design and (bio)physicochemical properties, their fate in biological media and cells, and their potential for cancer treatment; and finally reflect on the role of animal models to predict their behavior in humans.

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KW - Biological media

KW - Hybrid nanomaterials

KW - Knowledge gaps

KW - New modality

KW - Physicochemical property

KW - Surface design

KW - Therapeutic intervention

KW - Animals

KW - Biocompatible Materials

KW - Humans

KW - Molecular Imaging

KW - Nanomedicine

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JO - ACS Nano

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Nanoparticles for imaging, sensing, and therapeutic intervention

Abstract

Keywords

UN SDGs

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