3q. abnormalities define a subtype of myeloid malignancies characterized by similar clinical, morphologic and cytogenetic features, poor response to therapy and short survival. Trilineage myelodysplasia, affecting particularly the megakaryocytic line, is usually present. We describe five patients with myeloid malignancies and 3q26 abnormalities in whom bone marrow biopsy showed reticulin fibrosis, a feature rarely reported.
|Publication status||Published - 1 May 2000|
- 3q alterations
- Myeloid malignancies
- Reticulin fibrosis