TY - JOUR
T1 - Mutagenicity studies on fenitrothion in Drosophila
AU - Velázquez, A.
AU - Xamena, N.
AU - Creus, A.
AU - Marcos, R.
PY - 1987/9/1
Y1 - 1987/9/1
N2 - To extend the data on the possible genotoxic effects of organophosphorus pesticides, the insecticide fenitrothion was tested for the induction of gene and chromosome mutations in male germ cells of Drosophila melanogaster. Sex-linked recessive lethals, total and partial sex-chromosome losses and non-disjunction were studied following different exposure methods: adult feeding, injection and larval feeding. In the tests assaying for recessive lethals, we used a MRA strain resistant to malathion. Our results indicate that fenitrothion, at concentrations ranging from 50 to 150 p.p.m., is unable to induce any kind of genetic damage in D. melanogaster, at least under the conditions of testing. © 1987 IRL Press Ltd.
AB - To extend the data on the possible genotoxic effects of organophosphorus pesticides, the insecticide fenitrothion was tested for the induction of gene and chromosome mutations in male germ cells of Drosophila melanogaster. Sex-linked recessive lethals, total and partial sex-chromosome losses and non-disjunction were studied following different exposure methods: adult feeding, injection and larval feeding. In the tests assaying for recessive lethals, we used a MRA strain resistant to malathion. Our results indicate that fenitrothion, at concentrations ranging from 50 to 150 p.p.m., is unable to induce any kind of genetic damage in D. melanogaster, at least under the conditions of testing. © 1987 IRL Press Ltd.
U2 - 10.1093/mutage/2.5.333
DO - 10.1093/mutage/2.5.333
M3 - Article
SN - 0267-8357
VL - 2
SP - 333
EP - 336
JO - Mutagenesis
JF - Mutagenesis
IS - 5
ER -