Multisystemic lymphoplasmacytic inflammation associated with PCV‐3 in wasting pigs

Jaume Alomar; Viviane Saporiti; Mònica Pérez; Diogo Gonçalvez; Marina Sibila; Joaquim Segalés

doi:10.1111/tbed.14260

Multisystemic lymphoplasmacytic inflammation associated with PCV‐3 in wasting pigs

Jaume Alomar, Viviane Saporiti, Mònica Pérez, Diogo Gonçalvez, Marina Sibila, Joaquim Segalés

Department of Animal Health and Anatomy

Research output: Contribution to journal › Article › Research › peer-review

10 Citations (Web of Science)

Abstract

Porcine circovirus 3 (PCV-3) has been detected in diseased and healthy pigs of different ages. Several reports have associated the agent with reproductive failure and mummified and stillborn piglets. One report from North America has proposed a consistent potential association with postweaning disorders. Thus, the present case report aimed to describe the histopathological lesions and their association with the presence of PCV-3 genome in postweaning pigs showing growth-retardation and thrown-back ears. All affected animals displayed multi-organic lymphoplasmacytic periarteritis, lymphocytic myocarditis and/or lymphoplasmacytic meningoencephalitis. PCV-3 genetic material was detected by in situ hybridization within the lesions and confirmed by PCV-3 real-time quantitative PCR detection in tissues. This study represents the first report of PCV-3 associated with clinical disease in postweaning pigs in Europe.

Original language	English
Number of pages	6
Journal	Transboundary and emerging diseases
Volume	68
Issue number	6
DOIs	https://doi.org/10.1111/tbed.14260
Publication status	Published - 6 Nov 2021

Keywords

in situ hybridization
myocarditis
periarteritis
pig
porcine circovirus 3
postweaning
SYNDROME PMWS
DISEASE

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10.1111/tbed.14260

https://ddd.uab.cat/record/251959

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title = "Multisystemic lymphoplasmacytic inflammation associated with PCV‐3 in wasting pigs",

abstract = "Porcine circovirus 3 (PCV-3) has been detected in diseased and healthy pigs of different ages. Several reports have associated the agent with reproductive failure and mummified and stillborn piglets. One report from North America has proposed a consistent potential association with postweaning disorders. Thus, the present case report aimed to describe the histopathological lesions and their association with the presence of PCV-3 genome in postweaning pigs showing growth-retardation and thrown-back ears. All affected animals displayed multi-organic lymphoplasmacytic periarteritis, lymphocytic myocarditis and/or lymphoplasmacytic meningoencephalitis. PCV-3 genetic material was detected by in situ hybridization within the lesions and confirmed by PCV-3 real-time quantitative PCR detection in tissues. This study represents the first report of PCV-3 associated with clinical disease in postweaning pigs in Europe.",

keywords = "in situ hybridization, myocarditis, periarteritis, pig, porcine circovirus 3, postweaning, SYNDROME PMWS, DISEASE",

author = "Jaume Alomar and Viviane Saporiti and M{\`o}nica P{\'e}rez and Diogo Gon{\c c}alvez and Marina Sibila and Joaquim Segal{\'e}s",

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T1 - Multisystemic lymphoplasmacytic inflammation associated with PCV‐3 in wasting pigs

AU - Alomar, Jaume

AU - Saporiti, Viviane

AU - Pérez, Mònica

AU - Gonçalvez, Diogo

AU - Sibila, Marina

AU - Segalés, Joaquim

PY - 2021/11/6

Y1 - 2021/11/6

N2 - Porcine circovirus 3 (PCV-3) has been detected in diseased and healthy pigs of different ages. Several reports have associated the agent with reproductive failure and mummified and stillborn piglets. One report from North America has proposed a consistent potential association with postweaning disorders. Thus, the present case report aimed to describe the histopathological lesions and their association with the presence of PCV-3 genome in postweaning pigs showing growth-retardation and thrown-back ears. All affected animals displayed multi-organic lymphoplasmacytic periarteritis, lymphocytic myocarditis and/or lymphoplasmacytic meningoencephalitis. PCV-3 genetic material was detected by in situ hybridization within the lesions and confirmed by PCV-3 real-time quantitative PCR detection in tissues. This study represents the first report of PCV-3 associated with clinical disease in postweaning pigs in Europe.

AB - Porcine circovirus 3 (PCV-3) has been detected in diseased and healthy pigs of different ages. Several reports have associated the agent with reproductive failure and mummified and stillborn piglets. One report from North America has proposed a consistent potential association with postweaning disorders. Thus, the present case report aimed to describe the histopathological lesions and their association with the presence of PCV-3 genome in postweaning pigs showing growth-retardation and thrown-back ears. All affected animals displayed multi-organic lymphoplasmacytic periarteritis, lymphocytic myocarditis and/or lymphoplasmacytic meningoencephalitis. PCV-3 genetic material was detected by in situ hybridization within the lesions and confirmed by PCV-3 real-time quantitative PCR detection in tissues. This study represents the first report of PCV-3 associated with clinical disease in postweaning pigs in Europe.

KW - in situ hybridization

KW - myocarditis

KW - periarteritis

KW - pig

KW - porcine circovirus 3

KW - postweaning

KW - SYNDROME PMWS

KW - DISEASE

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DO - 10.1111/tbed.14260

M3 - Article

C2 - 34328681

VL - 68

IS - 6

ER -

Multisystemic lymphoplasmacytic inflammation associated with PCV‐3 in wasting pigs

Abstract

Keywords

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