Multiplicity-edited 1H-1H TOCSY experiment

Pau Nolis; Teodor Parella

doi:10.1002/mrc.4695

Multiplicity-edited ¹H-¹H TOCSY experiment

Pau Nolis, Teodor Parella

Department of Chemistry

Research output: Contribution to journal › Article › Research

3 Citations (Scopus)

Abstract

Copyright © 2017 John Wiley & Sons, Ltd. A 1H-1H total correlation spectroscopy (TOCSY) experiment incorporating 13C multiplicity information is proposed. In addition, broadband 1H homodecoupling in the indirect dimension can be implemented using a perfect BIRD module that affords exclusive 1H chemical shift evolution with full decoupling of all heteronuclear and homonuclear (including 2JHH) coupling constants. As a complement to the normal TOCSY and the recent PSYCHE-TOCSY experiments, this novel multiplicity-edited TOCSY experiment distinguishes between CH/CH3 (phased up) and CH2 (phased down) cross-peaks, which facilitates resonance analysis and assignment.

Original language	English
Pages (from-to)	976-982
Journal	Magnetic Resonance in Chemistry
Volume	56
DOIs	https://doi.org/10.1002/mrc.4695
Publication status	Published - 1 Oct 2018

Keywords

BIRD
broadband homodecoupling
carbon multiplicity
homodecoupled TOCSY
multiplicity-edited TOCSY
perfect BIRD
pure shift NMR
TOCSY

Access to Document

10.1002/mrc.4695

Cite this

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title = "Multiplicity-edited 1H-1H TOCSY experiment",

abstract = "Copyright {\textcopyright} 2017 John Wiley & Sons, Ltd. A 1H-1H total correlation spectroscopy (TOCSY) experiment incorporating 13C multiplicity information is proposed. In addition, broadband 1H homodecoupling in the indirect dimension can be implemented using a perfect BIRD module that affords exclusive 1H chemical shift evolution with full decoupling of all heteronuclear and homonuclear (including 2JHH) coupling constants. As a complement to the normal TOCSY and the recent PSYCHE-TOCSY experiments, this novel multiplicity-edited TOCSY experiment distinguishes between CH/CH3 (phased up) and CH2 (phased down) cross-peaks, which facilitates resonance analysis and assignment.",

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author = "Pau Nolis and Teodor Parella",

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AU - Parella, Teodor

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AB - Copyright © 2017 John Wiley & Sons, Ltd. A 1H-1H total correlation spectroscopy (TOCSY) experiment incorporating 13C multiplicity information is proposed. In addition, broadband 1H homodecoupling in the indirect dimension can be implemented using a perfect BIRD module that affords exclusive 1H chemical shift evolution with full decoupling of all heteronuclear and homonuclear (including 2JHH) coupling constants. As a complement to the normal TOCSY and the recent PSYCHE-TOCSY experiments, this novel multiplicity-edited TOCSY experiment distinguishes between CH/CH3 (phased up) and CH2 (phased down) cross-peaks, which facilitates resonance analysis and assignment.

KW - BIRD

KW - broadband homodecoupling

KW - carbon multiplicity

KW - homodecoupled TOCSY

KW - multiplicity-edited TOCSY

KW - perfect BIRD

KW - pure shift NMR

KW - TOCSY

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DO - 10.1002/mrc.4695

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