Multiple thromboemboli associated to two occult tumors: A case mimicking catastrophic antiphospholipid syndrome

Juan Muñoz-Ortego, Luisa Blanco Lopez, Jordi Carbonell Abello, Jordi Monfort Faure

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5 Citations (Scopus)

Abstract

Thromboembolic events tend to arise during the natural lifetime of tumors. However, multiple thromboemboli mimicking catastrophic antiphospholipid syndrome is quite rare as a first manifestation of a tumor. Herein we describe the case of a 51-year old woman that presented with multiple thromboemboli affecting her brain, lung and kidneys. Despite bolus administration of corticosteroids, anticoagulant therapy and immunoglobulin infusion treatment, the patient died. She had suffered from two occult tumors, which could not be identified premortem: a lung adenocarcinoma and an intrahepatic cholangiocarcinoma. This case underscores the importance of determining the underlying etiology behind multiple thromboemboli. The most important prognostic factor is rapid initiation of treatment of the multiple thromboemboli, emphasizing treatment of their etiology. © 2010 Société française de rhumatologie.
Original languageEnglish
Pages (from-to)405-408
JournalJoint Bone Spine
Volume78
Issue number4
DOIs
Publication statusPublished - 1 Jul 2011

Keywords

  • Antiphospholipid antibodies
  • Catastrophic antiphospholipid syndrome
  • Multiple thromboemboli
  • Occult tumors

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