Multiple Sclerosis: Epidemiologic, Clinical, and Therapeutic Aspects

Angela Vidal-Jordana, Xavier Montalban

Research output: Contribution to journalReview articleResearchpeer-review

22 Citations (Scopus)


© 2016 Elsevier Inc. Multiple sclerosis (MS) is a chronic autoimmune and degenerative disease of the central nervous system that affects young people. MS develops in genetically susceptible individuals exposed to different unknown triggering factors. Different phenotypes are described. About 15% of patients present with a primary progressive course and 85% with a relapsing-remitting course. An increasing number of disease-modifying treatments has emerged. Although encouraging, the number of drugs challenges the neurologist because each treatment has its own risk–benefit profile. Patients should be involved in the decision-making process to ensure good treatment and safety monitoring adherence.
Original languageEnglish
Pages (from-to)195-204
JournalNeuroimaging Clinics of North America
Issue number2
Publication statusPublished - 1 May 2017


  • Multiple sclerosis
  • Symptoms
  • Treatment


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