MRI criteria for MS in patients with clinically isolated syndromes

X. Montalban, M. Tintore, J. Swanton, F. Barkhof, F. Fazekas, M. Filippi, J. Frederiksen, L. Kappos, J. Palace, C. Polman, M. Rovaris, N. de Stefano, A. Thompson, T. Yousry, A. Rovira, D. H. Miller

Research output: Contribution to journalArticleResearchpeer-review

221 Citations (Scopus)


In recent years, criteria for the diagnosis of multiple sclerosis (MS) have changed, mainly due to the incorporation of new MRI criteria. While the new criteria are a logical step forward, they are complex and-not surprisingly-a good working knowledge of them is not always evident among neurologists and neuroradiologists. In some circumstances, several MRI examinations are needed to achieve an accurate and prompt diagnosis. This provides an incentive for continued efforts to refine the incorporation of MRI-derived information into the diagnostic workup of patients presenting with a clinically isolated syndrome. Within the European multicenter collaborative research network that studies MRI in MS (MAGNIMS), a workshop was held in London in November 2007 to review information that may simplify the existing MS diagnostic criteria, while maintaining a high specificity that is essential to minimize false positive diagnoses. New data that are now published were reviewed and discussed and together with a new proposal are integrated in this position paper. Neurology(R) 2010;74:427-434
Original languageEnglish
Pages (from-to)427-434
Number of pages8
Issue number5
Publication statusPublished - 2 Feb 2010


  • Suspected multiple-sclerosis
  • Diagnostic-criteria
  • Follow-up
  • Differential-diagnosis
  • Predict conversion
  • Evoked-potentials
  • Mcdonald criteria
  • Imaging criteria
  • In-vivo
  • Lesions


Dive into the research topics of 'MRI criteria for MS in patients with clinically isolated syndromes'. Together they form a unique fingerprint.

Cite this