A series of new chiral molecular tweezers, di-(R,R)-1-[10-(1-hydroxy-2,2,2- trifluoroethyl)-9-anthryl]-2,2,2-trifluoroethyl phthalate (2), isophthalate (3) and terephthalate (4), were synthesized and their structure studied by NMR and molecular mechanics. Their effectiveness as chiral solvating agents for the determination of the enantiomeric purity of chiral compounds using NMR was demonstrated. © 2009 Wiley-Liss, Inc.
|Publication status||Published - 1 Jun 2010|
- Chiral solvating agents
- Enantiomeric excess
- Molecular tweezers