TY - JOUR
T1 - Molecular polymorphism of the ABO blood group: A study in Poland, Spain, and Andorra
AU - Umbria, Miriam
AU - Cantons, Jordi
AU - Bruguera, Carmina
AU - Minias, Alina
AU - de Duró, Chantal Backes
AU - Catalano, Giulio
AU - Santos, Cristina
AU - Nogués, Ramon
AU - Aluja, Maria Pilar
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Objectives: The main goal of this study is to increase knowledge on the molecular level of the ABO blood group system in Europe by providing data for Poland, Spain, and Andorra populations. Methods: A total of 172 oral scrapings samples from individuals of Polish origin, 108 peripheral blood samples of autochthonous individuals from the province of Zamora (Spain), and 81 peripheral blood samples from individuals with Andorran origin, were analyzed. Molecular characterization of the allelic variants was performed by the analysis of exons 6 and 7 of the ABO gene. Results: Seven common alleles were identified, namely: A101, A102, A201, B101, O01, O02, and O03. Less common variants (O05, O09, O21, O26, O06, O11, and O12), were also detected. Conclusions: The results obtained contribute to the knowledge of the molecular European ABO map, and are discussed in regard to the allelic frequency reported by other Caucasian and Asian populations. Am. J. Hum. Biol. 26:556-558, 2014. © 2014 Wiley Periodicals, Inc.
AB - Objectives: The main goal of this study is to increase knowledge on the molecular level of the ABO blood group system in Europe by providing data for Poland, Spain, and Andorra populations. Methods: A total of 172 oral scrapings samples from individuals of Polish origin, 108 peripheral blood samples of autochthonous individuals from the province of Zamora (Spain), and 81 peripheral blood samples from individuals with Andorran origin, were analyzed. Molecular characterization of the allelic variants was performed by the analysis of exons 6 and 7 of the ABO gene. Results: Seven common alleles were identified, namely: A101, A102, A201, B101, O01, O02, and O03. Less common variants (O05, O09, O21, O26, O06, O11, and O12), were also detected. Conclusions: The results obtained contribute to the knowledge of the molecular European ABO map, and are discussed in regard to the allelic frequency reported by other Caucasian and Asian populations. Am. J. Hum. Biol. 26:556-558, 2014. © 2014 Wiley Periodicals, Inc.
U2 - 10.1002/ajhb.22544
DO - 10.1002/ajhb.22544
M3 - Article
SN - 1042-0533
VL - 26
SP - 556
EP - 558
JO - American Journal of Human Biology
JF - American Journal of Human Biology
IS - 4
ER -