Molecular Epidemiology of Trypanosomatids and Trypanosoma cruzi in Primates from Peru

Esar Aysanoa, Pedro Mayor, A. Patricia Mendoza, Carlos M. Zariquiey, E. Angelo Morales, Jocelyn G. Pérez, Mark Bowler, Julio A. Ventocilla, Carlos González, G. Christian Baldeviano, Andrés G. Lescano

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

© 2017, EcoHealth Alliance. We determined the prevalence rate and risk of infection of Trypanosoma cruzi and other trypanosomatids in Peruvian non-human primates (NHPs) in the wild (n = 126) and in different captive conditions (n = 183). Blood samples were collected on filter paper, FTA cards, or EDTA tubes and tested using a nested PCR protocol targeting the 24Sα rRNA gene. Main risk factors associated with trypanosomatid and T. cruzi infection were genus and the human–animal context (wild vs captive animals). Wild NHPs had higher prevalence of both trypanosomatids (64.3 vs 27.9%, P OpenSPiltSPi 0.001) and T. cruzi (8.7 vs 3.3%, P = 0.057), compared to captive NHPs, suggesting that parasite transmission in NHPs occurs more actively in the sylvatic cycle. In terms of primate family, Pitheciidae had the highest trypanosomatid prevalence (20/22, 90.9%) and Cebidae had the highest T. cruzi prevalence (15/117, 12.8%). T. cruzi and trypanosomatids are common in Peruvian NHPs and could pose a health risk to human and animals that has not been properly studied.
Original languageEnglish
Pages (from-to)732-742
JournalEcoHealth
Volume14
Issue number4
DOIs
Publication statusPublished - 1 Dec 2017

Keywords

  • Chagas
  • Epidemiology
  • Non-human primates
  • Prevalence
  • Trypanosoma cruzi
  • Trypanosomatids

Fingerprint Dive into the research topics of 'Molecular Epidemiology of Trypanosomatids and Trypanosoma cruzi in Primates from Peru'. Together they form a unique fingerprint.

Cite this