Milk C-reactive protein in canine mastitis

Iosif Vasiu, Roman Dąbrowski, Silvia Martinez-Subiela, Jose J. Ceron, Anna Wdowiak, Raul Alexandru Pop, Florinel Gheorghe Brudaşcă, Josep Pastor, Asta Tvarijonaviciute

    Research output: Contribution to journalArticleResearchpeer-review

    10 Citations (Scopus)


    © 2017 Elsevier B.V. Presence of mastitis in lactating bitches can become life threatening for both the bitch and pups. The aim of the present study was to evaluate a possible utility of C-reactive protein (CRP) in both milk and serum for canine mastitis diagnosis. Our study showed that milk CRP levels ranged between 0.1 and 4.9 μg/mL and from 0.3 to 40.0 μg/mL in healthy and diseased bitches (P < 0.01), respectively, while serum CRP levels ranged between 2.0 and 8.6 μg/mL and between 0.3 and 162.3 μg/mL in healthy and diseased bitches (P < 0.01), respectively. Milk and serum CRP levels were higher in both clinical and subclinical mastitis when compared with healthy controls (P < 0.05 in all cases). However, no significant differences were recorded in CRP concentrations between clinical and subclinical cases. Based on these results, it could be concluded that serum and milk CRP could be useful in order to diagnose canine mastitis.
    Original languageEnglish
    Pages (from-to)41-44
    JournalVeterinary Immunology and Immunopathology
    Publication statusPublished - 1 Apr 2017


    • C-reactive protein
    • Dog
    • Mastitis
    • Milk
    • Serum


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