Micro and nanomotors in diagnostics

Andrzej Chałupniak, Eden Morales-Narváez, Arben Merkoçi

    Research output: Contribution to journalReview articleResearchpeer-review

    66 Citations (Scopus)

    Abstract

    © 2015 Elsevier B.V. Synthetic micro/nanomotors are tiny devices than can be self-propelled or externally powered in the liquid phase by different types of energy source including but not limited to: catalytic, magnetic or acoustic. Showing a myriad of mechanical movements, building block materials, sizes, shapes and propulsion mechanisms micro/nanomotors are amenable to diagnostics and therapeutics. Herein we describe the most relevant micro/nanomotors, their fabrication pathways, propulsion strategies as well as in vivo and in vitro applications related with oligonucleotides, proteins, cells and tissues. We also discuss the main challenges in these applications such as the influence of complex media and toxicity issues as well as future perspectives.
    Original languageEnglish
    Pages (from-to)104-116
    JournalAdvanced Drug Delivery Reviews
    Volume95
    DOIs
    Publication statusPublished - 1 Dec 2015

    Keywords

    • Biosensors
    • Drug delivery systems
    • In vitro bioassays
    • Micromotors
    • Nanomotors
    • Nanowires

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    Chałupniak, A., Morales-Narváez, E., & Merkoçi, A. (2015). Micro and nanomotors in diagnostics. Advanced Drug Delivery Reviews, 95, 104-116. https://doi.org/10.1016/j.addr.2015.09.004