For several years the medical treatment of active ankylosing spondylitis (AS) has been NSAID. Steroids have not shown efficacy. In 1981 Mintz et al reported that methylprednisolone pulse therapy had an excellent effect in patients with AS. Six patients with active AS and no efficacy with NSAID were treated with 1 gram methyl prednisolone daily given intravenously for three successive days. Significant pain relief were clearly demonstrated. We conclude that intravenous MPPT is a useful treatment in patients with active AS when NSAID are not effective.
|Journal||Revista Espanola de Reumatologia|
|Publication status||Published - 1 Mar 1997|