Meningeal carcinomatosis as the first manifestation of a transitional cell carcinoma of the bladder

Jordi Bruna Escuer; Íñigo Rojas-Marcos; Sergio Martínez-Yelamos; Isabel Català; Antonio Villader; Carmen Galán; Jurek Krupinski; Francisco Rubio

doi:10.1023/A:1023781604980

Meningeal carcinomatosis as the first manifestation of a transitional cell carcinoma of the bladder

Jordi Bruna Escuer, Íñigo Rojas-Marcos, Sergio Martínez-Yelamos, Isabel Català, Antonio Villader, Carmen Galán, Jurek Krupinski, Francisco Rubio

Department of Cellular Biology, Physiology and Immunology

Research output: Contribution to journal › Article › Research › peer-review

21 Citations (Scopus)

Abstract

Meningeal carcinomatosis (MC) as first manifestation of a transitional cell carcinoma (TCC) of the bladder is rare. We report a 66-year-old man, smoker, who presented with two episodes of secondarily generalized partial motor seizures. The routine blood test, brain computed tomography (CT) scan, brain magnetic resonance imaging and electroencephalogram were normal. Cerebral spinal fluid (CSF) revealed a significant pleocytosis and a morphology compatible with non-differentiated non-small cell carcinoma. Broncofiberscopy, gastrofiberscopy, thoracicoabdominopelvic CT-scan and bone scintigraphy were normal but the urine cytology revealed malignant cells similar to those found in the CSF. TCC was diagnosed by cystoscopy and later necropsy confirmed the MC of this tumor. In this report we review the literature and analyze patient survival.

Original language	English
Pages (from-to)	63-67
Journal	Journal of Neuro-Oncology
Volume	63
Issue number	1
DOIs	https://doi.org/10.1023/A:1023781604980
Publication status	Published - 1 May 2003

Keywords

Bladder tumor
CSF cytology
Meningeal carcinomatosis
Seizures
Transitional cell carcinoma
Urine cytology

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title = "Meningeal carcinomatosis as the first manifestation of a transitional cell carcinoma of the bladder",

abstract = "Meningeal carcinomatosis (MC) as first manifestation of a transitional cell carcinoma (TCC) of the bladder is rare. We report a 66-year-old man, smoker, who presented with two episodes of secondarily generalized partial motor seizures. The routine blood test, brain computed tomography (CT) scan, brain magnetic resonance imaging and electroencephalogram were normal. Cerebral spinal fluid (CSF) revealed a significant pleocytosis and a morphology compatible with non-differentiated non-small cell carcinoma. Broncofiberscopy, gastrofiberscopy, thoracicoabdominopelvic CT-scan and bone scintigraphy were normal but the urine cytology revealed malignant cells similar to those found in the CSF. TCC was diagnosed by cystoscopy and later necropsy confirmed the MC of this tumor. In this report we review the literature and analyze patient survival.",

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AU - Bruna Escuer, Jordi

AU - Rojas-Marcos, Íñigo

AU - Martínez-Yelamos, Sergio

AU - Català, Isabel

AU - Villader, Antonio

AU - Galán, Carmen

AU - Krupinski, Jurek

AU - Rubio, Francisco

PY - 2003/5/1

Y1 - 2003/5/1

N2 - Meningeal carcinomatosis (MC) as first manifestation of a transitional cell carcinoma (TCC) of the bladder is rare. We report a 66-year-old man, smoker, who presented with two episodes of secondarily generalized partial motor seizures. The routine blood test, brain computed tomography (CT) scan, brain magnetic resonance imaging and electroencephalogram were normal. Cerebral spinal fluid (CSF) revealed a significant pleocytosis and a morphology compatible with non-differentiated non-small cell carcinoma. Broncofiberscopy, gastrofiberscopy, thoracicoabdominopelvic CT-scan and bone scintigraphy were normal but the urine cytology revealed malignant cells similar to those found in the CSF. TCC was diagnosed by cystoscopy and later necropsy confirmed the MC of this tumor. In this report we review the literature and analyze patient survival.

AB - Meningeal carcinomatosis (MC) as first manifestation of a transitional cell carcinoma (TCC) of the bladder is rare. We report a 66-year-old man, smoker, who presented with two episodes of secondarily generalized partial motor seizures. The routine blood test, brain computed tomography (CT) scan, brain magnetic resonance imaging and electroencephalogram were normal. Cerebral spinal fluid (CSF) revealed a significant pleocytosis and a morphology compatible with non-differentiated non-small cell carcinoma. Broncofiberscopy, gastrofiberscopy, thoracicoabdominopelvic CT-scan and bone scintigraphy were normal but the urine cytology revealed malignant cells similar to those found in the CSF. TCC was diagnosed by cystoscopy and later necropsy confirmed the MC of this tumor. In this report we review the literature and analyze patient survival.

KW - Bladder tumor

KW - CSF cytology

KW - Meningeal carcinomatosis

KW - Seizures

KW - Transitional cell carcinoma

KW - Urine cytology

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DO - 10.1023/A:1023781604980

M3 - Article

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EP - 67

JO - Journal of Neuro-Oncology

JF - Journal of Neuro-Oncology

IS - 1

ER -

Meningeal carcinomatosis as the first manifestation of a transitional cell carcinoma of the bladder

Abstract

Keywords

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