Meiotic and synaptonemal complex studies in a 14/21 translocation carrier

F. Vidal; C. Templado; J. Navarro; S. Marina; J. Egozcue

doi:https://doi.org/10.1111/j.1365-2605.1982.tb00229.x

Meiotic and synaptonemal complex studies in a 14/21 translocation carrier

F. Vidal, C. Templado, J. Navarro, S. Marina, J. Egozcue

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Abstract

Meiotic studies in a sterile carrier of a 14/21 translocation showed a meiotic arrest, with degeneration of primary spermatocytes. Silver staining of pachytene cells revealed the presence of a trivalent. Its synaptonemal complex was quite similar to that described in previous light and electron microscopy studies in mammalian species. The observation of a trivalent with pairing in trans‐configuration and the presence of desynaptic synaptonemal complexes in early pachytene could explain the relatively high incidence of non‐disjunction in human D/G translocations and the spermatogenic disintegration sometimes seen in these cases. Copyright © 1982, Wiley Blackwell. All rights reserved

Original language	English
Pages (from-to)	21-26
Journal	International Journal of Andrology
Volume	5
DOIs	https://doi.org/10.1111/j.1365-2605.1982.tb00229.x
Publication status	Published - 1 Jan 1982

Keywords

centric fusion
meiotic studies
synaptonemal complex

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title = "Meiotic and synaptonemal complex studies in a 14/21 translocation carrier",

abstract = "Meiotic studies in a sterile carrier of a 14/21 translocation showed a meiotic arrest, with degeneration of primary spermatocytes. Silver staining of pachytene cells revealed the presence of a trivalent. Its synaptonemal complex was quite similar to that described in previous light and electron microscopy studies in mammalian species. The observation of a trivalent with pairing in trans‐configuration and the presence of desynaptic synaptonemal complexes in early pachytene could explain the relatively high incidence of non‐disjunction in human D/G translocations and the spermatogenic disintegration sometimes seen in these cases. Copyright {\textcopyright} 1982, Wiley Blackwell. All rights reserved",

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AU - Templado, C.

AU - Navarro, J.

AU - Marina, S.

AU - Egozcue, J.

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AB - Meiotic studies in a sterile carrier of a 14/21 translocation showed a meiotic arrest, with degeneration of primary spermatocytes. Silver staining of pachytene cells revealed the presence of a trivalent. Its synaptonemal complex was quite similar to that described in previous light and electron microscopy studies in mammalian species. The observation of a trivalent with pairing in trans‐configuration and the presence of desynaptic synaptonemal complexes in early pachytene could explain the relatively high incidence of non‐disjunction in human D/G translocations and the spermatogenic disintegration sometimes seen in these cases. Copyright © 1982, Wiley Blackwell. All rights reserved

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