Abstract
Meiotic studies in a sterile carrier of a 14/21 translocation showed a meiotic arrest, with degeneration of primary spermatocytes. Silver staining of pachytene cells revealed the presence of a trivalent. Its synaptonemal complex was quite similar to that described in previous light and electron microscopy studies in mammalian species. The observation of a trivalent with pairing in trans‐configuration and the presence of desynaptic synaptonemal complexes in early pachytene could explain the relatively high incidence of non‐disjunction in human D/G translocations and the spermatogenic disintegration sometimes seen in these cases. Copyright © 1982, Wiley Blackwell. All rights reserved
Original language | English |
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Pages (from-to) | 21-26 |
Journal | International Journal of Andrology |
Volume | 5 |
DOIs | |
Publication status | Published - 1 Jan 1982 |
Keywords
- centric fusion
- meiotic studies
- synaptonemal complex