Meiotic and synaptonemal complex studies in a 14/21 translocation carrier

F. Vidal, C. Templado, J. Navarro, S. Marina, J. Egozcue

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51 Citations (Scopus)

Abstract

Meiotic studies in a sterile carrier of a 14/21 translocation showed a meiotic arrest, with degeneration of primary spermatocytes. Silver staining of pachytene cells revealed the presence of a trivalent. Its synaptonemal complex was quite similar to that described in previous light and electron microscopy studies in mammalian species. The observation of a trivalent with pairing in trans‐configuration and the presence of desynaptic synaptonemal complexes in early pachytene could explain the relatively high incidence of non‐disjunction in human D/G translocations and the spermatogenic disintegration sometimes seen in these cases. Copyright © 1982, Wiley Blackwell. All rights reserved
Original languageEnglish
Pages (from-to)21-26
JournalInternational Journal of Andrology
Volume5
DOIs
Publication statusPublished - 1 Jan 1982

Keywords

  • centric fusion
  • meiotic studies
  • synaptonemal complex

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