Mechanism of the gold-catalyzed cyclopropanation of alkenes with 1,6-enynes

Patricia Pérez-Galán, Elena Herrero-Gómez, Daniel T. Hog, Nolwenn J.A. Martin, Feliu Maseras, Antonio M. Echavarrenx

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Abstract

The gold(I)-catalyzed intermolecular cyclopropanation of alkenes with 1,6-enynes is an electrophilic process, which is mechanistically related to the well-known Simmons-Smith reaction proceeding through zinc carbenoids. This cyclopropanation is stereospecific, even in cases where the reaction was found to proceed stepwise. © The Royal Society of Chemistry 2011.
Original languageEnglish
Pages (from-to)141-149
JournalChemical Science
Volume2
Issue number1
DOIs
Publication statusPublished - 9 May 2011

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    Pérez-Galán, P., Herrero-Gómez, E., Hog, D. T., Martin, N. J. A., Maseras, F., & Echavarrenx, A. M. (2011). Mechanism of the gold-catalyzed cyclopropanation of alkenes with 1,6-enynes. Chemical Science, 2(1), 141-149. https://doi.org/10.1039/c0sc00335b