MDMA-assisted psychotherapy using low doses in a small sample of women with chronic posttraumatic stress disorder

José Carlos Bouso, Rick Doblin, Magí Farré, Miguel Ángel Alcázar, Gregorio Gómez-Jarabo

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77 Citations (Scopus)

Abstract

The purpose of this study was to investigate the safety of different doses of MDMA-assisted psychotherapy administered in a psychotherapeutic setting to women with chronic PTSD secondary to a sexual assault, and also to obtain preliminary data regarding efficacy. Although this study was originally planned to include 29 subjects, political pressures led to the closing of the study before it could be finished, at which time only six subjects had been treated. Preliminary results from those six subjects are presented here. We found that low doses of MDMA (between 50 and 75 mg) were both psychologically and physiologically safe for all the subjects. Future studies in larger samples and using larger doses are needed in order to further clarify the safety and efficacy of MDMA in the clinical setting in subjects with PTSD. © 2008 Taylor and Francis Group, LLC.
Original languageEnglish
Pages (from-to)225-236
JournalJournal of Psychoactive Drugs
Volume40
Issue number3
DOIs
Publication statusPublished - 1 Jan 2008

Keywords

  • MDMA
  • MDMA psychotherapy
  • Posttraumatic stress disorder
  • PTSD
  • Safety

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