Mathematical modelling of sequential determinations by flow-injection sandwich techniques

J. L. Montesinos; J. Bartrolí; M. Poch; M. del Valle; J. L.F.C. Lima; A. N. Araujo

doi:10.1016/S0003-2670(00)83539-4

Mathematical modelling of sequential determinations by flow-injection sandwich techniques

J. L. Montesinos, J. Bartrolí, M. Poch, M. del Valle, J. L.F.C. Lima, A. N. Araujo

Department of Chemistry

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Abstract

Preliminary results obtained in the evaluation of a mathematical model for flow-injection systems, including chemical kinetics, with an eight-way injection valve are presented. The use of this kind of injection valve permits the insertion of the sample bolus between two different reagent solutions (sandwich techniques). The model considers the system as a tubular reactor with axially dispersed plug flow. As an example for systems with chemical reaction, the enzymatic determination of glucose was chosen. The parameters of the model (dispersion coefficients and reaction rate constants) were experimentally evaluated by using a tracer or by unidirectional optimization, respectively. The effect of different parameters of the flow system on the analytical signal for one analyte and one reagent was simulated, and the model results are compared with experimental data obtained under the same conditions. © 1990.

Original language	English
Pages (from-to)	67-74
Journal	Analytica Chimica Acta
Volume	234
Issue number	C
DOIs	https://doi.org/10.1016/S0003-2670(00)83539-4
Publication status	Published - 1 Jan 1990

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title = "Mathematical modelling of sequential determinations by flow-injection sandwich techniques",

abstract = "Preliminary results obtained in the evaluation of a mathematical model for flow-injection systems, including chemical kinetics, with an eight-way injection valve are presented. The use of this kind of injection valve permits the insertion of the sample bolus between two different reagent solutions (sandwich techniques). The model considers the system as a tubular reactor with axially dispersed plug flow. As an example for systems with chemical reaction, the enzymatic determination of glucose was chosen. The parameters of the model (dispersion coefficients and reaction rate constants) were experimentally evaluated by using a tracer or by unidirectional optimization, respectively. The effect of different parameters of the flow system on the analytical signal for one analyte and one reagent was simulated, and the model results are compared with experimental data obtained under the same conditions. {\textcopyright} 1990.",

author = "Montesinos, {J. L.} and J. Bartrol{\'i} and M. Poch and {del Valle}, M. and Lima, {J. L.F.C.} and Araujo, {A. N.}",

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T1 - Mathematical modelling of sequential determinations by flow-injection sandwich techniques

AU - Montesinos, J. L.

AU - Bartrolí, J.

AU - Poch, M.

AU - del Valle, M.

AU - Lima, J. L.F.C.

AU - Araujo, A. N.

PY - 1990/1/1

Y1 - 1990/1/1

N2 - Preliminary results obtained in the evaluation of a mathematical model for flow-injection systems, including chemical kinetics, with an eight-way injection valve are presented. The use of this kind of injection valve permits the insertion of the sample bolus between two different reagent solutions (sandwich techniques). The model considers the system as a tubular reactor with axially dispersed plug flow. As an example for systems with chemical reaction, the enzymatic determination of glucose was chosen. The parameters of the model (dispersion coefficients and reaction rate constants) were experimentally evaluated by using a tracer or by unidirectional optimization, respectively. The effect of different parameters of the flow system on the analytical signal for one analyte and one reagent was simulated, and the model results are compared with experimental data obtained under the same conditions. © 1990.

AB - Preliminary results obtained in the evaluation of a mathematical model for flow-injection systems, including chemical kinetics, with an eight-way injection valve are presented. The use of this kind of injection valve permits the insertion of the sample bolus between two different reagent solutions (sandwich techniques). The model considers the system as a tubular reactor with axially dispersed plug flow. As an example for systems with chemical reaction, the enzymatic determination of glucose was chosen. The parameters of the model (dispersion coefficients and reaction rate constants) were experimentally evaluated by using a tracer or by unidirectional optimization, respectively. The effect of different parameters of the flow system on the analytical signal for one analyte and one reagent was simulated, and the model results are compared with experimental data obtained under the same conditions. © 1990.

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DO - 10.1016/S0003-2670(00)83539-4

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VL - 234

SP - 67

EP - 74

JO - Analytica Chimica Acta

JF - Analytica Chimica Acta

IS - C

ER -

Mathematical modelling of sequential determinations by flow-injection sandwich techniques

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