Maternal and neonatal hair and breast milk in the assessment of perinatal exposure to drugs of abuse

Xavier Joya; Roberta Pacifici; Judith Salat-Batlle; Oscar Garciá-Algar; Simona Pichini

doi:10.4155/bio.15.60

Maternal and neonatal hair and breast milk in the assessment of perinatal exposure to drugs of abuse

Xavier Joya, Roberta Pacifici, Judith Salat-Batlle, Oscar Garciá-Algar, Simona Pichini

Department of Paediatrics, Obstetrics and Gynaecology and Preventive Medicine and Public Health

Research output: Contribution to journal › Article › Research › peer-review

22 Citations (Scopus)

Abstract

© 2015 Future Science Ltd. Perinatal exposure to one or more drugs of abuse can affect the neonate temporarily or permanently. In addition to meconium, the evaluation of perinatal exposure to drugs of abuse has been achieved by testing biological matrices coming from the newborn (neonatal hair) and from the pregnant or nursing mother (maternal hair and breast milk). These matrices have the advantage of noninvasive collection and account for a sizable time window of active and passive exposure. Sensitive and specific analytical methods are required to determine minute amounts of drugs of abuse and metabolites in these matrices. The present manuscript reviews the newest analytical methods developed to detect drugs of abuse as well as ethanol biomarkers in maternal and neonatal hair and breast milk.

Original language	English
Pages (from-to)	1273-1297
Journal	Bioanalysis
Volume	7
Issue number	10
DOIs	https://doi.org/10.4155/bio.15.60
Publication status	Published - 1 Jan 2015

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AU - Pacifici, Roberta

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AU - Garciá-Algar, Oscar

AU - Pichini, Simona

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AB - © 2015 Future Science Ltd. Perinatal exposure to one or more drugs of abuse can affect the neonate temporarily or permanently. In addition to meconium, the evaluation of perinatal exposure to drugs of abuse has been achieved by testing biological matrices coming from the newborn (neonatal hair) and from the pregnant or nursing mother (maternal hair and breast milk). These matrices have the advantage of noninvasive collection and account for a sizable time window of active and passive exposure. Sensitive and specific analytical methods are required to determine minute amounts of drugs of abuse and metabolites in these matrices. The present manuscript reviews the newest analytical methods developed to detect drugs of abuse as well as ethanol biomarkers in maternal and neonatal hair and breast milk.

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Maternal and neonatal hair and breast milk in the assessment of perinatal exposure to drugs of abuse

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