Management of recurrent head and neck cancer: variables related to salvage surgery

Laura Gañán, Montserrat López, Jacinto García, Eduard Esteller, Miquel Quer, Xavier León

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Abstract

© 2016, Springer-Verlag Berlin Heidelberg. After a local and/or regional recurrence of head and neck squamous cell carcinoma (HNSCC) not all patients are candidates to salvage treatment. The objective of this study was to identify the variables related to performance of salvage surgery with curative intent in these patients. We performed a retrospective study of 1088 HNSCC patients with a local and/or regional recurrence. According to a multivariate analysis, the variables related to performance of salvage surgery were the Karnofsky index, the location and extension of the primary tumor, the initial treatment, the disease-free interval between treatment of the initial tumor and diagnosis of the recurrence, and the year the recurrence was diagnosed. Considering salvage surgery as the dependent variable, the results of a recursive partitioning analysis defined four categories of patients in function of the category of local and regional extension of the initial tumor, the location of the primary tumor, the initial treatment and the disease-free interval between treatment of the initial tumor and diagnosis of the recurrence.
Original languageEnglish
Pages (from-to)4417-4424
JournalEuropean Archives of Oto-Rhino-Laryngology
Volume273
Issue number12
DOIs
Publication statusPublished - 1 Dec 2016

Keywords

  • Head and neck cancer
  • Local recurrence
  • Regional recurrence
  • Salvage surgery
  • Salvage treatment

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