A description is given of a woman of 37 yr who suffered from a malignant pheochromocytoma which secreted principally noradrenalin. A hemodynamic study was carried out after exsanguination which showed the vascular effect of the great increase of the peripheral resistance, the cardiac index, and the systolic and minute volume. A study was also made of the secretion of insulin under basal conditions and under the effects of phentolamine and propranolol. A moderated normalization was obtained of the curve of glycemia with only discrete modification of the levels of insulinemia during the alpha block with phentolamine. The short evolution of the disease is emphasized as well as the inefficacy of the cytostatics and the beneficial effect of phenoxybenzamine which attenuated the clinical manifestations of the disease.
|Publication status||Published - 1 Jan 1974|