Malignant epithelioid schwannoma affecting the trigeminal nerve of a dog

Marti Pumarola Batlle, Sonia Añor Torres, Daniel Borras Murcia, I. Ferrer

    Research output: Contribution to journalArticleResearchpeer-review

    39 Citations (Scopus)

    Abstract

    A malignant epithelioid schwannoma was diagnosed affecting the trigeminal nerve of an 11-year-old dog. Neurologic abnormalities included an altered mental status, ataxia, left head tilt, postural reaction deficits of all four limbs, a pronounced left masticatory muscle atrophy, and absent left facial sensation. Histologically, a densely arranged epithelioid population with a very high mitotic index was surrounded by a spindle-shaped cell proliferation characteristic of schwannomas. Both cell populations stained positively for vimentin, but only spindle cells were occassionally positive for S-100 protein. The histologic and immunohistochemical features of this tumor were consistent with those found in human epithelioid schwannomas.
    Original languageEnglish
    Pages (from-to)434-436
    JournalVeterinary Pathology
    Volume33
    Issue number4
    DOIs
    Publication statusPublished - 1 Jan 1996

    Keywords

    • Dog
    • Malignant epithelioid schwannoma
    • Trigeminal nerve

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