LymPHOS 2.0: An update of a phosphosite database of primary human T cells

Tien Dung Nguyen, Oriol Vidal-Cortes, Oscar Gallardo, Joaquin Abian, Montserrat Carrascal

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    8 Citations (Scopus)

    Abstract

    © 2015 The Author(s) 2015. Published by Oxford University Press. LymPHOS is a web-oriented database containing peptide and protein sequences and spectrometric information on the phosphoproteome of primary human T-Lymphocytes. Current release 2.0 contains 15 566 phosphorylation sites from 8273 unique phosphopeptides and 4937 proteins, which correspond to a 45-fold increase over the original database description. It now includes quantitative data on phosphorylation changes after time-dependent treatment with activators of the TCR-mediated signal transduction pathway. Sequence data quality has also been improved with the use of multiple search engines for database searching. LymPHOS can be publicly accessed at http://www.lymphos.org.
    Original languageEnglish
    Article numberbav115
    JournalDatabase
    Volume2015
    Issue number1
    DOIs
    Publication statusPublished - 1 Jan 2015

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