Lung cancer in HIV-infected patients in the combination antiretroviral treatment era

José Moltó, Teresa Moran*, Guillem Sirera, Bonaventura Clotet

*Corresponding author for this work

Research output: Contribution to journalReview articleResearchpeer-review

15 Citations (Scopus)

Abstract

The advent of combination antiretroviral treatment (cART) has been followed by a decrease in HIV-associated morbidity and mortality, but also by an apparent increase in the incidence of non-AIDSdefining cancers (NADCs). The risk of lung cancer is substantially higher in HIV-infected patients than in the general population, in part due to aging and tobacco use, and it is the most frequent NADC. The management of lung cancer in HIV-infected patients has some peculiarities that need to be taken into account. This review focuses on the epidemiology, risk factors, and clinical management of lung cancer in HIV-infected patients. In addition, screening tools and future perspectives are also discussed.
Original languageEnglish
Pages (from-to)678-688
Number of pages11
JournalTranslational Lung Cancer Research
Volume4
Issue number6
DOIs
Publication statusPublished - 28 Dec 2015

Keywords

  • Antiretroviral treatment
  • HIV infection
  • Lung cancer
  • Non-AIDS-defining cancers (NADCs)

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