LTCC microflow analyzers with monolithic integration of thermal control

Cynthia S. Martínez-Cisneros, Núria Ibáñez-García, Francisco Valdés, Julián Alonso

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)


Recently, the low temperature co-fired ceramics technology has shown to be an excellent alternative to silicon-based microfabrication techniques for the production of three-dimensional structures using a multi-layer approach. This enables the integration of several unitary operations of a classical analytical process and also the integration of sensors, actuators and electronics in the same substrate. In this work, we show the integration of the actuators and the sensors needed for the control of temperature inside a miniaturized fluidic device. The proposed device presents enough thermal accuracy to be used in chemical systems where temperature control is a crucial factor, such as enzyme reactions or polymerase chain reaction systems. © 2007 Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)63-70
JournalSensors and Actuators, A: Physical
Issue number1
Publication statusPublished - 20 Jul 2007


  • Electronics
  • Fluidics
  • LTCC
  • Miniaturization
  • Temperature control


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