Low frequency of exon 3 PTPN11 mutations in adult de novo acute myeloid leukemia. Analysis of a consecutive series of 173 patients

Josep Nomdedéu, Maria T. Carricondo, Adriana Lasa, Granada Perea, Ana Aventin, Jorge Sierra

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Abstract

A total of 173 samples obtained from adult patients with de novo acute myeloid leukemia (AML) were assayed for exon 3 PTPN11 mutations by single strand conformation polymorphism (SSCP) analysis and direct sequencing. Only three monocytic leukemias had point mutations (1.73%).
Original languageEnglish
Pages (from-to)412-413
JournalHaematologica
Volume90
Issue number3
Publication statusPublished - 1 Mar 2005

Keywords

  • Acute myeloid leukemia
  • Adults PTPN11

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