Long-term results of tacrolimus in cyclosporine- and prednisone-dependent myasthenia gravis

J. M. Ponseti*, J. Azem, J. M. Fort, M. López-Cano, R. Vilallonga, M. Buera, C. Cervera, M. Armengol

*Corresponding author for this work

Research output: Contribution to journalArticleResearchpeer-review

64 Citations (Scopus)

Abstract

Seventy-nine patients with cyclosporine- and prednisone-dependent myasthenia gravis (MG) after thymectomy received tacrolimus for a mean of 2.5 ± 0.8 years. Prednisone was withdrawn in all but two patients. Anti-acetylcholine antibodies and MG score for disease severity decreased significantly and muscular strength increased by 39%. Complete stable remission was achieved in 5% of patients and pharmacologic remission in 87.3%. All patients resumed full activities of daily living.

Original languageAmerican English
Pages (from-to)1641-1643
Number of pages3
JournalNeurology
Volume64
Issue number9
DOIs
Publication statusPublished - 10 May 2005

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