Long-term results of tacrolimus in cyclosporine- and prednisone-dependent myasthenia gravis

J. M. Ponseti; J. Azem; J. M. Fort; M. López-Cano; R. Vilallonga; M. Buera; C. Cervera; M. Armengol

doi:https://doi.org/10.1212/01.WNL.0000160392.32894.6D

Long-term results of tacrolimus in cyclosporine- and prednisone-dependent myasthenia gravis

J. M. Ponseti, J. Azem, J. M. Fort, M. López-Cano, R. Vilallonga, M. Buera, C. Cervera, M. Armengol

Department of Surgery

Research output: Contribution to journal › Article › Research › peer-review

72 Citations (Scopus)

Abstract

Seventy-nine patients with cyclosporine- and prednisone-dependent myasthenia gravis (MG) after thymectomy received tacrolimus for a mean of 2.5 ± 0.8 years. Prednisone was withdrawn in all but two patients. Anti-acetylcholine antibodies and MG score for disease severity decreased significantly and muscular strength increased by 39%. Complete stable remission was achieved in 5% of patients and pharmacologic remission in 87.3%. All patients resumed full activities of daily living.

Original language	English
Pages (from-to)	1641-1643
Number of pages	3
Journal	Neurology
Volume	64
Issue number	9
DOIs	https://doi.org/10.1212/01.WNL.0000160392.32894.6D https://doi.org/10.1212/01.WNL.0000160392.32894.6D
Publication status	Published - 10 May 2005

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title = "Long-term results of tacrolimus in cyclosporine- and prednisone-dependent myasthenia gravis",

abstract = "Seventy-nine patients with cyclosporine- and prednisone-dependent myasthenia gravis (MG) after thymectomy received tacrolimus for a mean of 2.5 ± 0.8 years. Prednisone was withdrawn in all but two patients. Anti-acetylcholine antibodies and MG score for disease severity decreased significantly and muscular strength increased by 39%. Complete stable remission was achieved in 5% of patients and pharmacologic remission in 87.3%. All patients resumed full activities of daily living.",

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T1 - Long-term results of tacrolimus in cyclosporine- and prednisone-dependent myasthenia gravis

AU - Ponseti, J. M.

AU - Azem, J.

AU - Fort, J. M.

AU - López-Cano, M.

AU - Vilallonga, R.

AU - Buera, M.

AU - Cervera, C.

AU - Armengol, M.

PY - 2005/5/10

Y1 - 2005/5/10

N2 - Seventy-nine patients with cyclosporine- and prednisone-dependent myasthenia gravis (MG) after thymectomy received tacrolimus for a mean of 2.5 ± 0.8 years. Prednisone was withdrawn in all but two patients. Anti-acetylcholine antibodies and MG score for disease severity decreased significantly and muscular strength increased by 39%. Complete stable remission was achieved in 5% of patients and pharmacologic remission in 87.3%. All patients resumed full activities of daily living.

AB - Seventy-nine patients with cyclosporine- and prednisone-dependent myasthenia gravis (MG) after thymectomy received tacrolimus for a mean of 2.5 ± 0.8 years. Prednisone was withdrawn in all but two patients. Anti-acetylcholine antibodies and MG score for disease severity decreased significantly and muscular strength increased by 39%. Complete stable remission was achieved in 5% of patients and pharmacologic remission in 87.3%. All patients resumed full activities of daily living.

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U2 - https://doi.org/10.1212/01.WNL.0000160392.32894.6D

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SN - 0028-3878

VL - 64

SP - 1641

EP - 1643

JO - Neurology

JF - Neurology

IS - 9

ER -

Long-term results of tacrolimus in cyclosporine- and prednisone-dependent myasthenia gravis

Abstract

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