The clinical aspects of and experimental procedures performed on a young woman with localized heat urticaria are described. The few cases reported in the literature do not appear to coincide. Circulation blockage, locally produced or due to a pressure cuff, was the only experimental procedure that prevented the appearance of the reaction. Participation of the kininogen-kinin system in the genesis of increased vascular permeability seems to be a possibility in our patient, who also showed an exaggerated local response to histamine and to the histamine releaser, Compound 48/80. © 1973, American Medical Association. All rights reserved.
|Journal||Archives of Dermatology|
|Publication status||Published - 1 Jan 1973|