The authors retrospectively review the hepatic function of 23 patients with chronic juvenile arthritis to evaluate the role of the previous administration of antiflammatory agents, as well as the importance of histopathological data in the diagnostic processes of the disease. Aminotranspherases were high in 10 patients, five of whom had liver enlargement and were receiving anti-inflammatory drugs, while the other four were given the same treatment and did not have liver enlargement. Of the 13 patients without elevated aminotranspherases, 11 were receiving anti-inflammatory drugs and seven presented liver enlargement. In four cases a hepatic biopsy was done because of the onset of the illness as a fever of unknown origin. In general alterations of the hepatic function are considered the result of anti-inflammatory treatment, or they may be due to reactive hepatitis with nonspecific periportal infiltrates, of no use in the diagnosis.
|Journal||Revista Espanola de Reumatologia|
|Publication status||Published - 1 Jan 1980|