Liposomes and other vesicular systems: Structural characteristics, methods of preparation, and use in nanomedicine

Elisa Elizondo, Evelyn Moreno, Ingrid Cabrera, Alba Córdoba, Santiago Sala, Jaume Veciana, Nora Ventosa

    Research output: Chapter in BookChapterResearchpeer-review

    51 Citations (Scopus)

    Abstract

    Vesicular systems, especially liposomes, have generated a great deal of interest as intelligent materials for the delivery of bioactive molecules since they can be used as sensitive containers that respond to external stimuli, such as pressure, pH, temperature, or concentration changes in the medium, triggering modifications in their supramolecular structure. The control of the nanostructure - particle size and size distribution, membrane morphology, and supramolecular organization - of these self-assembled systems is of profound importance for their application in drug delivery and the discovery of new nanomedicines. This chapter will describe the chemical structure of vesicles and their pharmacological properties, conventional and new vesicle preparation methods and structural characterization, as well as their use in the rational design and fabrication of nanomedicines. © 2011 Elsevier Inc.
    Original languageEnglish
    Title of host publicationProgress in Molecular Biology and Translational Science
    Pages1-52
    Number of pages51
    Volume104
    DOIs
    Publication statusPublished - 1 Jan 2011

    Keywords

    • Drug carriers
    • Drug delivery
    • Green processing
    • Liposomes
    • Nanomedicine
    • Small unilamellar vesicles
    • Supercritical fluids
    • Vesicles

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